March 3, 2009

Dear shareholders,

As the President says “These are trying times”, and our economy, financial markets and national pride have seen better days.

Many companies’ stock prices have been battered by the current market conditions, and Torvec has not gone unscathed, although the selling volume is almost insignificant.

We still remain confident in our direction and of our ultimate success. We at Torvec, want to thank its shareholders for their resolve and continued support as we all hope for our country’s swift return to “normalcy”.

We have been busy since our shareholders meeting on January 28th, and wanted to inform you that all programs and potential programs mentioned at the annual meeting continue to move forward along the lines of what was disclosed at the annual meeting. New opportunities have also developed. Once we have more information that we are allowed to divulge, you, our shareholders, will be the first to know.

Sincerely,

James Gleasman
CEO